Seizures in systemic lupus erythematosus: A scoping review

Systemic lupus erythematosus is a systemic autoimmune disease that affects the central nervous system, either by direct neuronal damage, injury to brain vessels, or pathogenic mechanisms indirectly induced immune related production and deposition of complexes. The prevalence explicit episodes seizures among SLE patients, varies from 2 8%. In some cases, patients with positivity for antiphospholipid anti-?2 glycoprotein antibodies are found be more prone exhibit compared seronegative other subjects at risk carries gene abnormalities codifying ion channels. exclusion vasculitis thrombosis required accurate treatment, imaging studies alternative sequences mandatory in known who present seizure. Several statements regarding SLE-related seizure remain decoded. this scoping review we analyzed published information about prevalence, pathogenesis, clinical characteristics, diagnostic therapeutic manifest seizure, our objective provide useful prompt diagnosis individualized treatment.